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Wide-band laser photo-acoustic spectroscopy and machine learning for breath air analysis

Yury V. Kistenev,1 , Alexey V. Borisov,1, Vladimir V.Prishepa,1, Igor K. Lednev,2, Han Jin, 3,4
1 Tomsk State University, Tomsk 634050, Russian Federation
2 University at Albany, SUNY, Albany, NY 12222, USA
3 Institute of Micro-Nano Science and Technology, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China
4 National Engineering Research Center for Nanotechnology, Shanghai, 200241, P. R. China

Abstract

The report is devoted to applications of wide tuning range photo-acoustic laser spectroscopy and machine learning for breath air analysis to detect a specific disease. Breath air analysis can be conducted through the chemical-composition-based and pattern-recognition-based approaches. For the former approach implementation, we use deep neural networks [1] and original chemometrics’ methods: (a) a combination of the standard addition method with multivariate curve resolution called HAMAND [2]; (b) criterium based on reducing a spectrum complexity (RSC) [3] to provide exhaled air chemical composition. The latter approach is typical for supervised machine learning algorithms. We will compare both approaches.

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Speaker

Yury V. Kistenev
Tomsk State University, Tomsk, 634050, Russia
Russia

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