Development of Sub-millimeter Multifunction Optical Endoscopes

Abstract

With multiple mechanisms of contrast, high sensitivity, high resolution, and the possibility to create miniature, inexpensive devices, light-based techniques have tremendous potential to positively impact cancer detection and survival. Many organs of the body can be reached in a minimally-invasive fashion with small flexible endoscopes. Some organs, such as the fallopian tubes and ovaries, require extremely miniature (sub-mm) and flexible endoscopes to avoid tissue cutting. Additionally, some modalities, such as side-viewing optical coherence tomography (OCT), are naturally suited to miniature endoscopes, whereas others like forward-viewing reflectance or fluorescence imaging, may require performance tradeoffs. The development of small, robust and fiber-delivered advanced light sources, miniature fiber bundles, and sensitive detectors has aided the development of novel miniature endoscopes. In this talk, I will discuss our recent advancements in multimodality endoscopes, such as a 0.8 mm diameter endoscope with OCT and multispectral fluorescence imaging.

Speaker

Jennifer Barton
University of Arizona
United States of America

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