RELAXATION AND OSMOTIC-INDUCED SLOW STRAIN MAPPING IN BIOLOGICAL TISSUES BY OPTICAL COHERENCE ELASTOGRAPHY
Yu.A. Alexandrovskaya1, O.I. Baum1, A.A. Sovetskiy2, A.L. Matveyev2, L.A. Matveev2, V.Yu. Zaitsev2
1-Institute of Photon Technologies, Federal Scientific Research Center “Crystallography and Photonics”, Russian Academy of Sciences, Troitsk, Moscow, Russia
2-Institute of Applied Physics of the Russian Academy of Sciences, Nizhny Novgorod, Russia
Abstract
Imaging of slow deformations in biological tissues may contribute to study and reveal many complex processes, such as fluid flow, mechanical stress growth and relaxation, formation of interstitial pores caused by application of external force. Here the new method of strain mapping based on analysis of complex-valued OCT signal for real-time cartilage visualization is presented. The tissue is modified with laser radiation and/or immersion agents. The evolution of strain caused by their modifying effects is analyzed. The aims of the study include the development of medical control system for fabrication of stable cartilaginous implants.
Speaker
Alexandrovskaya Yulia
Institute of Photon Technologies, Federal Scientific Research Center “Crystallography and Photonics”, Russian Academy of Sciences
Russia
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