Influence of interactions of lanthanide-based nanocomplexes with surrounding molecules on the luminescent properties of nanoparticles in suspensions.
A. Fedyanina (1), S. Burikov (1), O. Sarmanova (1), S. V. Kuznetsov (2), T. Dolenko (1)
(1) - Moscow State University, Department of Physics, Moscow, Russia
(2) - Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia
Abstract
Nanocomplexes doped with rare-earth elements (REE) are believed to be a promising class of materials. Being often used as luminescent markers, they have found a wide application in biomedicine. This is caused by the fact that such complexes allow to realize anti-stokes luminescence in case of being excited in the near infrared (NIR) region. Biological tissues themselves - skin, muscles, connective tissues - have luminescence properties. The advantage of using IR excitation lies in its ability to induce the luminescence of REE-based nanocomplexes, but not luminescence of biological environment. In other words, the problem of separating useful signal of biosensors against the autoluminescence background is eliminated.
Particles revealing anti-stokes luminescence are called up-conversion nanoparticles (UCNPs). Their luminescence properties depend on a variety of factors: the power of the exciting radiation, the size of nanocomplexes, etc. Variability of these parameters keeps UCNPs from strengthening the positions in practical medicine. Moreover, being injected in real biological environment (blood, lymph, etc.), particles interact with different types of biomacromolecules and cells’ components. That is the reason why one should, firstly, study the interactions of nanoparticles and surrounding molecules and, secondly, learn more about the influence of these interactions on the UCNPs’ luminescence.
This work is devoted to the study of the impact of environmental molecules on UCNPs’ luminescence properties in aqueous suspensions. Complex of NaYF4:Yb/Tm, consisting of NaYF4 crystalline matrix and co-doped with Yb3+ and Tm3+ as sensitizer and activator, suspended in a variety of solvents (water, ethanol, methanol, water-ethanol solutions and DMSO) were used as research objects.
During the experiment, anti-stokes luminescence spectra of UCNPs were obtained using excitation by 980 nm diode laser and analyzed. This paper presents the results of studying the interactions between the crystal matrix of REE-nanocomplexes and surrounding molecules and the degree of influence of these interactions on the photoluminescent properties of UCNPs.
This study was supported by Russian Foundation for Basic Research (Project №18-02-01023).
Speaker
Anna Fedyanina
Moscow State University, Department of Physics
Russia
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