Diagnostics of synchronization between the systems of autonomic regulation of cardiovascular function using synchrogram analysis
E.I. Borovkova, Saratov State Medical University, Saratov State University, Russia; A.S. Karavaev, Saratov State Medical University, Saratov State University, Saratov Branch of the Institute of RadioEngineering and Electronics of Russian Academy of Sciences, Russia; A.R. Kiselev, Saratov State Medical University, Saratov State University, Russia; V.I. Gridnev, Saratov State Medical University, Saratov State University, Russia; A.N. Khramkov, Saratov State University, Russia; E.P. Chernets, Saratov State University, Russia; E.V. Navrotskaya, Saratov State University, Russia; M.D. Prokhorov, Saratov State University, Saratov Branch of the Institute of RadioEngineering and Electronics of Russian Academy of Sciences, Russia; Bezruchko B.P., Saratov State University, Russia;
Abstract
In the course of the ROC analysis, we tested the synchrogram analysis method to study the synchronization of the systems of autonomic regulation of of heart rate and mean arterial pressure.
To test the method, we used artificial test data for which information about the boundaries of the synchronization intervals was known. The data reproduced the statistics of distributions of the length of synchronization intervals and areas of non-synchronous behavior, fluctuations of instantaneous oscillation frequencies and properties of phase noise in systems of autonomic regulation of heart rate and mean arterial pressure.
As a result, we identified a range of method parameters providing sensitivity at the level of 0.7 and specificity at the level of 0.3 and showed that the method is promising for solving problems of medical diagnostics.
Speaker
Borovkova E.I.
Saratov State Medical University, Saratov State University, Russia
Russia
Discussion
Ask question
