Optical properties of functionally relevant human brain areas
Ksenia Achkasova, Privolzhsky Research Medical University, Nizhny Novgorod, Russia; Alexander Moiseev, Institute of Applied Physics Russian Academy of Science, Nizhny Novgorod, Russia; Konstantin Yashin, Privolzhsky Research Medical University, Nizhny Novgorod, Russia; Elena Kiseleva, Privolzhsky Research Medical University, Nizhny Novgorod, Russia; Eugenia Bederina, Privolzhsky Research Medical University, Nizhny Novgorod, Russia; Anna Epishkina, Privolzhsky Research Medical University, Nizhny Novgorod, Russia; Natalia Gladkova, Privolzhsky Research Medical University, Nizhny Novgorod, Russia
Abstract
Surgical resection is one of the treatment options for patients with brain tumors. It is necessary to detect white matter and receive information about its condition in order to prevent damage of healthy fiber tracts during surgery. Cross-polarization optical coherence tomography (CP OCT) is a so-called functional extension of OCT that seems to have benefits in intraoperative use in brain cancer surgery. The aim of the study was to search for the possible difference in the CP OCT signal obtained from different white matter regions and to compare optical features of different normal brain tissue types. CP OCT study of grey and white matter was conducted on 8 post-mortem human brain specimens (4 left and 4 right hemispheres). Qualitative assessment of three-dimensional OCT data included three optical coefficients calculation. Statistical analysis of obtained data allowed finding the statistically significant difference between different white matter regions as well as between different normal brain tissue types.
Speaker
Achkasova Ksenia
Privolzhsky Research Medical University
Russia
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