akzotov@hotmail.com
A K. Zotov (1), I. N. Dolganova(1), K. I. Zaytsev(3), I.A. Shikunova(1), N. A. Naumova(1,3) , L. P. Safonova (2), P. V. Aleksandrova (2), V.N. Kurlov (1)
1) Institute of Solid State Physics of the Russian Academy of Sciences, Chernogolovka 142432, Russia;
2) Bauman Moscow State Technical University, Moscow 105005, Russia;
3) Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow 119991, Russia;
Abstract
Cryodestruction is one of the promising medical techniques, which is applied in such fields as oncology, dermatology, urology, gynecology, cosmetology, etc. for removal of tissues and particularly, neoplasms. Unfortunately, it is accompanied with the certain risks of damaging healthy tissues, since the monitoring of the ice-ball formation during tissue freezing is a severe problem. In order to solve this problem, the diffuse reflectance spectroscopy and terahertz (THz) pulsed spectroscopy were suggested for control the freezing depth. For this purpose, a special cryoapplicator, based on sapphire shaped crystal, was proposed. Due to high transparency in a wide spectral range, chemical resistance, and high thermal conductivity at the cryogenic temperatures, sapphire is an appropriate material for cryosurgery. Moreover, the technique of sapphire shaped crystal growth enables fabrication of applicators of complex shapes and cross-sections, which can be combined with optical fibers or applied as THz waveguides. The experimental results demonstrated the ability of the suggested techniques to control the cryodestruction proces
Speaker
A K. Zotov
Institute of Solid State Physics of the Russian Academy of Sciences
Russia
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